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HMG-1 Polyclonal Antibody, 50ul[BT-AP04140] Cellular Cultivation & Health Management the encoded protein binds to

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HMG-1 Polyclonal Antibody, 50ul[BT-AP04140] Cellular Cultivation & Health Management the encoded protein binds toHMGB1 encodes high mobility group box 1 that belongs to the High Mobility Group box superfamily. The encoded non histone, nuclear DNA binding protein regulates transcription, and is involved in organization of DNA. This protein plays a role in several cellular processes, including inflammation, cell differentiation and tumor cell migration. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript

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Description

the encoded protein binds to the promoter region of TGFB-responsive genes and recruits a nuclear repressor complex

DTX3 functions as an E3 ubiquitin ligase (Takeyama et al

extracellular protein with protease inhibitor-like domains whose expression is suppressed strongly in many tumors and cells transformed by various kinds of oncogenes

which is thought to alter the structure and function of the receptor complex

HMG-1 Polyclonal Antibody, 50ul[BT-AP04140] Cellular Cultivation & Health Management the encoded protein binds toHMGB1 encodes high mobility group box 1 that belongs to the High Mobility Group box superfamily. The encoded non histone, nuclear DNA binding protein regulates transcription, and is involved in organization of DNA. This protein plays a role in several cellular processes, including inflammation, cell differentiation and tumor cell migration. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript

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