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Blood sugar: Eat around injection time and keep fast-acting carbohydrate available, since IGF-1 LR3 can lower blood glucose

Step 4: Stay consistent

In addition to IGF pathways, anti-tumor effects on PI3K/AKT/mTOR and MAPK/ERK pathways with metformin exposure were observed, leading to the upregulation of markers of cell cycle arrest, apoptosis, and autophagy and downregulation of markers associated with senescence and the inhibition of cell migration (Lee et al., 2018