NMBR Polyclonal Antibody, 50ul[BT-AP06070] Drug Development and Evaluation The mouse gene is located

The mouse gene is located in double minute (DM) chromatin particles

A highly similar duplicated copy of this gene is found in close proximity on the long arm of chromosome 10

with similarity to the globular (non-collagen-like) domain of complement component C1qB

This protein| along with TAB1 and MAP3K7| also participates in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF-kappaB (TNFRSF11A/RANK)| which may regulate the development and function of osteoclasts

NMBR Polyclonal Antibody, 50ul[BT-AP06070] Drug Development and Evaluation The mouse gene is locatedNMBR encodes a 7 transmembrane G protein coupled receptor that binds neuromedin B, which is a growth factor and mitogen for gastrointestinal epithelial tissue and for normal and neoplastic lung. This receptor may play a role in smooth muscle contraction, neuronal responses, and the regulation of cell growth. Antagonists of this receptor have a potential therapeutic use in inhibiting tumor cell growth. Polymorphisms in NMBR may be associated with a