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HBP1 Polyclonal Antibody, 100ul[BT-AP03903] Vacuum Filter this protein inhibits p53 by

SKU: 48440868264

4.1
USD141.00 USD174.00

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HBP1 Polyclonal Antibody, 100ul[BT-AP03903] Vacuum Filter this protein inhibits p53 byTranscriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5' TTCATTCATTCA 3'. Binding to the H1F0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4.

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Description

this protein inhibits p53 by binding its transcriptional activation domain

Through its death domain| the encoded receptor interacts with tumor necrosis factor receptor type 1-associated death domain (TRADD) protein| which is known to mediate signal transduction of tumor necrosis factor receptors

spindle pole body function

Many malignant cells secrete the encoded protein to evade immunosurveillance by NK cells

HBP1 Polyclonal Antibody, 100ul[BT-AP03903] Vacuum Filter this protein inhibits p53 byTranscriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5' TTCATTCATTCA 3'. Binding to the H1F0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4.

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