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Disruption of mitochondrial complex I induces progressive Parkinsonism

We merged genes from the three databases to create a gene set for each pathway (Additional file 1: Tables S2S4), resulting in 5325, 2557, and 3435 genes for Most Studied Pathways, Gene-Associated Pathways, and Popular Pathways, respectively

Whats the smallest set of changes that moves the needle

Summary Keywords appetite-regulatory peptides, addictive drugs, dependence, reward, dopamine Citation Tufvesson-Alm M, Shevchouk OT and Jerlhag E (2023) Insight into the role of the gut-brain axis in alcohol-related responses: Emphasis on GLP-1, amylin, and ghrelin