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LIFR Polyclonal Antibody, 100ul Recombinant Protein Expression The proteins of this family

SKU: 44783465532

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LIFR Polyclonal Antibody, 100ul Recombinant Protein Expression The proteins of this familyLIFR encodes leukemia inhibitory factor receptor alpha that belongs to the type I cytokine receptor family. This protein combines with a high affinity converter subunit, gp130, to form a receptor complex that mediates the action of the leukemia inhibitory factor, a polyfunctional cytokine that is involved in cellular differentiation, proliferation and survival in the adult and the embryo. Mutations in this gene cause Schwartz Jampel syndrome type 2, a

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Description

The proteins of this family are thought to be involved in the formation of filamentous networks in the extracellular matrices of various tissues

This protein is located in the mitochondrial matrix and catalyzes the cleavage of the leader peptides of precursor proteins newly imported into the mitochondria| though it only functions as part of a heterodimeric complex

This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor

The encoded protein is found in the nucleus but translocates to the cytoplasm upon phosphorylation and activation

LIFR Polyclonal Antibody, 100ul Recombinant Protein Expression The proteins of this familyLIFR encodes leukemia inhibitory factor receptor alpha that belongs to the type I cytokine receptor family. This protein combines with a high affinity converter subunit, gp130, to form a receptor complex that mediates the action of the leukemia inhibitory factor, a polyfunctional cytokine that is involved in cellular differentiation, proliferation and survival in the adult and the embryo. Mutations in this gene cause Schwartz Jampel syndrome type 2, a

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