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Rescued with Wnt agonist BML-284 demonstrated a central role of this pathway by recovering caudatin-mediated inhibition of glycolysis and EMT (Epithelial-Mesenchymal Transition) markers (Table 1, Row 2)

Current treatments for AD, such as acetylcholinesterase inhibitors (e.g., donepezil) and NMDA receptor antagonists (e.g., memantine), provide symptomatic relief but do not halt or reverse disease progression