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The FDA has approved a number of peptides as medications, including insulin for diabetics who dont naturally produce it and human growth hormone for children with developmental disorders caused by low levels of the hormone

Factors increasing the production of reactive species can be internal, such as inflammation, or external such as pollution, UV exposure, xenobiotic compounds, and cigarette smoke

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5-oxoproline is an intermediate in the gamma-glutamyl pathway, which is the metabolic cycle responsible for generating glutathione and membrane transport of amino acids into the cytosol [4]