Cables1 Polyclonal Antibody, 100ul Micro Centrifuge Tubes A deletion downstream of SOST

A deletion downstream of SOST

see MIM 179508

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The encoded protein contains a KRAB (Kruppel-associated box) domain -A box and a SET (Su(var)3-9| Enhancer-of-zeste| Trithorax) domain and may function as a histone methyltransferase

Cables1 Polyclonal Antibody, 100ul Micro Centrifuge Tubes A deletion downstream of SOSTCABLES1 encodes a protein (Cdk5 and Abl enzyme substrate 1) involved in regulation of the cell cycle through interactions with several cyclin dependent kinases. One study (PMID: 16177568) reported aberrant splicing of transcripts from this gene which results in removal of the cyclin binding domain only in human cancer cells, and reduction in gene expression was shown in colorectal cancers (PMID: 17982127). Multiple transcript variants encoding