SMAD7 Polyclonal Antibody, 50ul Peptide Library NCOR1 is located between the

NCOR1 is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17

The encoded protein directly interacts with a GTPase activating protein that functions downstream of the small G protein Ral

These read-through transcripts are ubiquitously present and up-regulated during granulocyte differentiation

this gene encodes a protein that is not closely related to other known growth factors

SMAD7 Polyclonal Antibody, 50ul Peptide Library NCOR1 is located between theThe protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding, this complex translocates to the cytoplasm, where it interacts with TGF beta receptor type 1 (TGFBR1), leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3). Several transcript variants encoding