Integrin Beta2 Polyclonal Antibody, 20ul[BT-AP04586] Cell Dissociation The encoded protein downregulates the

The encoded protein downregulates the innate immune response and therefore provides a therapeutic target for enhancing its antimicrobial activity against foreign agents

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B cells and cytotoxic T cells

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Integrin Beta2 Polyclonal Antibody, 20ul[BT-AP04586] Cell Dissociation The encoded protein downregulates theITGB2 encodes an integrin beta chain, which combines with multiple different alpha chains to form different integrin heterodimers. Integrins are integral cell surface proteins that participate in cell adhesion as well as cell surface mediated signalling. The integrin subunit beta 2 plays an important role in immune response and defects in this gene cause leukocyte adhesion deficiency. Alternative splicing results in multiple transcript variants.