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Dysferlin Polyclonal Antibody, 50ul ADME SELP encodes a 140 kDa

SKU: 20239772183

4.1
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Dysferlin Polyclonal Antibody, 50ul ADME SELP encodes a 140 kDaThe protein encoded by DYSF (dysferlin) belongs to the ferlin family and is a skeletal muscle protein found associated with the sarcolemma. It is involved in muscle contraction and contains C2 domains that play a role in calcium mediated membrane fusion events, suggesting that it may be involved in membrane regeneration and repair. In addition, the protein encoded by DYSF binds caveolin 3, a skeletal muscle membrane protein which is important in the

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Description

SELP encodes a 140 kDa protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells

F2RL3 is activated by thrombin and trypsin

Upregulated expression of this gene in astroglial cells upon exposure to lipopolysaccharides suggests a function for the encoded protein in the brain

Low expression in heart

Dysferlin Polyclonal Antibody, 50ul ADME SELP encodes a 140 kDaThe protein encoded by DYSF (dysferlin) belongs to the ferlin family and is a skeletal muscle protein found associated with the sarcolemma. It is involved in muscle contraction and contains C2 domains that play a role in calcium mediated membrane fusion events, suggesting that it may be involved in membrane regeneration and repair. In addition, the protein encoded by DYSF binds caveolin 3, a skeletal muscle membrane protein which is important in the

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