DNA Ligase IV(Phospho Thr650) Polyclonal Antibody, 50ul Protein Modification The enzyme has steroid 18-hydroxylase

The enzyme has steroid 18-hydroxylase activity to synthesize aldosterone and 18-oxocortisol as well as steroid 11 beta-hydroxylase activity

This gene has also been linked to diabetic nephropathy

Growth arrest-specific 1 plays a role in growth suppression

HMW-uPA can be further processed into the catalytically active low molecular weight urokinase-type plasminogen activator (LMW-uPA)

DNA Ligase IV(Phospho Thr650) Polyclonal Antibody, 50ul Protein Modification The enzyme has steroid 18-hydroxylaseThe protein encoded by this gene is a DNA ligase that joins single strand breaks in a double stranded polydeoxynucleotide in an ATP dependent reaction. This protein is essential for V(D)J recombination and DNA double strand break (DSB) repair through nonhomologous end joining (NHEJ). This protein forms a complex with the X ray repair cross complementing protein 4 (XRCC4), and further interacts with the DNA dependent protein kinase (DNA PK). Both XRCC4