B2LA1 Polyclonal Antibody, 50ul Biochemical Reagents Transcription adaptor P300/CBP (EP300/CREBBP) has

Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein| which is thought to be involved in the process of blocking IFN-alpha response by adenovirus

Mouse studies showed that the gene deficiency results in deafness and loss of the Sertoli cell epithelial phenotype in the testis

Binds to a large number of partners| usually by recognition of a phosphoserine or phosphothreonine motif

This gene has a paralog located in the nonrecombining region of the Y chromosome

B2LA1 Polyclonal Antibody, 50ul Biochemical Reagents Transcription adaptor P300/CBP (EP300/CREBBP) hasThis gene encodes a member of the BCL 2 protein family. The proteins of this family form hetero or homodimers and act as anti and pro apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription