XRN2 Polyclonal Antibody, 20ul Liquid Storage Consumables The TIR domain containing adaptor

The TIR domain containing adaptor protein encoded by TIRAP is a TIR adaptor protein involved in the TLR4 signaling pathway of the immune system

and reduced expression can suppress transforming growth factor-beta induced growth arrest

each encoding a protein (224-235 amino acids) with a hydrophobic leader sequence

It is thought to be a functional relative of PPAR-gamma coactivator 1 that activates mitochondrial biogenesis through NRF1 in response to proliferative signals

XRN2 Polyclonal Antibody, 20ul Liquid Storage Consumables The TIR domain containing adaptorXRN2 encodes a 5' 3' exonuclease that promotes transcription termination at cotranscriptional cleavage sites. Alternative splicing results in multiple transcript variants encoding different isoforms.