TTBK1 Rabbit Polyclonal Antibody, 100ul Immune Cell Preparation Autoantibodies against the encoded protein

Autoantibodies against the encoded protein have been detected in serum from patients with type 1 diabetes

Binds to the consensus calcium-response element CaRE1 5'-CTATTTCGAG-3' sequence

The protein encoded by this gene represents the alpha subunit

a transmembrane domain and a cytoplasmic domain that contains three immune-receptor tyrosine-based inhibitory motifs

TTBK1 Rabbit Polyclonal Antibody, 100ul Immune Cell Preparation Autoantibodies against the encoded proteinSummary: This gene belongs to the casein kinase 1 superfamily. The encoded protein is a neuron specific serine threonine and tyrosine kinase which regulates phosphorylation of tau a protein that associates with microtubule assemblies and stabilizes them. Genetic variants in this gene are associated with Alzheimer's disease.