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N-acetylcysteine and Sulodexide have been found to mitigate endothelial damage

IGF1 is a primary mediator of GH activity and directly influences muscle hypertrophy, protein synthesis, and nutrient partitioning (Yakar et al., Endocrinology )

In vivo investigations corroborated the in vitro results, demonstrating that Au@miR-183i NCs effectively targeted tumors, induced robust ICD, and significantly enhanced PD-L1 immunotherapy, finally eliciting a vigorous systemic anticancer immune response in mice models with HCC [317]