p53(Phospho Ser6) Polyclonal Antibody, 20ul Apoptosis & Autophagy Keratin type I cytoskeletal 19

Keratin type I cytoskeletal 19 encoded by KRT19 is a member of the keratin family

This protein binds to chromatin prior to DNA damage and is phosphorylated by the checkpoint kinase ATR following damage

When overexpressed in mammalian cells

which is a multiprotein complex located in the inner mitochondrial membrane

p53(Phospho Ser6) Polyclonal Antibody, 20ul Apoptosis & Autophagy Keratin type I cytoskeletal 19This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.