IKK Gamma Polyclonal Antibody, 50ul[BT-AP04426] Site-directed Mutagenesis As with many proteins

As with many proteins

This gene product is closely related to type XI collagen and it is possible that the collagen chains of types V and XI constitute a single collagen type with tissue-specific chain combinations

Contains 2 RING-type zinc fingers

the encoded protein has DNA glycosylase activity on DNA substrates containing oxidized pyrimidine residues and has apurinic/apyrimidinic lyase activity

IKK Gamma Polyclonal Antibody, 50ul[BT-AP04426] Site-directed Mutagenesis As with many proteinsIKBKG encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex, which activates NF kappaB resulting in activation of genes involved in inflammation, immunity, cell survival, and other pathways. Mutations in this gene result in incontinentia pigmenti, hypohidrotic ectodermal dysplasia, and several other types of immunodeficiencies. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome.