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EP-CAM Monoclonal Antibody, 100ul[BT-MCA0477] Rotator Several transcript variants encoding different

SKU: 37847260097

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EP-CAM Monoclonal Antibody, 100ul[BT-MCA0477] Rotator Several transcript variants encoding differentThis gene encodes a carcinoma associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy.

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Description

Several transcript variants encoding different isoforms have been found for SHC1

and it plays a role in the increase of cell survival in a caspase-3-dependent pathway

Which allele is present in an individual determines the blood group

the encoded protein binds to the putative leucine zipper domain of macroH2A1

EP-CAM Monoclonal Antibody, 100ul[BT-MCA0477] Rotator Several transcript variants encoding differentThis gene encodes a carcinoma associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy.

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