NPL4 Polyclonal Antibody, 100ul 3D Culture tissue specificity:Highly expressed in brain

tissue specificity:Highly expressed in brain

The protein encoded by this gene belongs to a subfamily of tyrosine kinase receptors with homology to Dictyostelium discoideum protein discoidin I in their extracellular domain

Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome

Mutations in this gene have been associated with autism and Asperger syndrome

NPL4 Polyclonal Antibody, 100ul 3D Culture tissue specificity:Highly expressed in brainBinds ubiquitinated proteins via its RanBP2 type zinc finger.,The ternary complex containing UFD1L, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. The NPLOC4 UFD1L VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope.,pathway: Protein degradation;