GALR3 Polyclonal Antibody, 50ul Cell Culture Flasks Beta subunit gene mutations lead

Beta subunit gene mutations lead to Sandhoff disease (GM2-gangliosidosis type II)

AFF1 encodes a member of the AF4/ lymphoid nuclear protein related to AF4/Fragile X E mental retardation syndrome family of proteins

The protein encoded by this gene plays an important role in the regulation of endosomal trafficking

and expression of some of the variants maybe independently regulated

GALR3 Polyclonal Antibody, 50ul Cell Culture Flasks Beta subunit gene mutations leadThe neuropeptide galanin modulates a variety of physiologic processes including cognition memory, sensory pain processing, hormone secretion, and feeding behavior. The human galanin receptors are G protein coupled receptors that functionally couple to their intracellular effector through distinct signaling pathways. GALR3 (galanin receptor 3) is found in many tissues and may be expressed as 1. 4 , 2. 4 and 5 kb transcripts.