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IKappaB-Beta Polyclonal Antibody, 50ul Bottles The 3-hydroxyisobutyrate dehydrogenase plays a

SKU: 47217527754

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IKappaB-Beta Polyclonal Antibody, 50ul Bottles The 3-hydroxyisobutyrate dehydrogenase plays aThe protein encoded by NFKBIB belongs to the NF kappa B inhibitor family, which inhibit NF kappa B by complexing with, and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF kappa B, which translocates to the nucleus to function as a transcription factor. Alternatively spliced transcript variants have been found

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Description

The 3-hydroxyisobutyrate dehydrogenase plays a critical role in the catabolism of L-valine by catalyzing the oxidation of 3-hydroxyisobutyrate to methylmalonate semialdehyde

Mutations in this gene are a cause of autosomal recessive congenital cataract-2 (CATC2)

The highly conserved RNA polymerase II transcription factor TFIID (see TAF1

This gene was identified by its ability to proteolytically cleave and activate the inactive precursor of interleukin-1

IKappaB-Beta Polyclonal Antibody, 50ul Bottles The 3-hydroxyisobutyrate dehydrogenase plays aThe protein encoded by NFKBIB belongs to the NF kappa B inhibitor family, which inhibit NF kappa B by complexing with, and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF kappa B, which translocates to the nucleus to function as a transcription factor. Alternatively spliced transcript variants have been found

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