MOB1(Phospho-Thr12) Rabbit Polyclonal Antibody, 20ul Long RNA Synthesis Hepatocyte nuclear factor 4-alpha encoded

Hepatocyte nuclear factor 4-alpha encoded by HNF4A is a nuclear transcription factor which binds DNA as a homodimer

Also involved in negative regulation of the cell cycle

One mechanism of foreign DNA restriction is deamination of foreign double-stranded DNA cytidines to uridines

Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway| thereby allowing activation and nuclear translocation of the NFKB complex

MOB1(Phospho-Thr12) Rabbit Polyclonal Antibody, 20ul Long RNA Synthesis Hepatocyte nuclear factor 4-alpha encodedThe protein encoded by this gene is a component of the Hippo signaling pathway which controls organ size and tumor growth by enhancing apoptosis. Loss of the encoded protein results in cell proliferation and cancer formation. The encoded protein is also involved in the control of microtubule stability during cytokinesis. Several transcript variants encoding different isoforms have been found for this gene.