CD13 Polyclonal Antibody, 50ul[BT-AP01347] Custom DNA Oligos Mutations in dysferlin| a protein

Mutations in dysferlin| a protein associated with the plasma membrane| can cause muscle weakness that affects both proximal and distal muscles

This calcium-dependent cell-cell adhesion molecule is comprised of five extracellular cadherin repeats

Down-regulated in melanoma tissue

and the encoded protein suppresses the androgen receptor and transforming growth factor beta signaling pathways though interactions with Smad proteins

CD13 Polyclonal Antibody, 50ul[BT-AP01347] Custom DNA Oligos Mutations in dysferlin| a proteinAminopeptidase N is located in the small intestinal and renal microvillar membrane, and also in other plasma membranes. In the small intestine aminopeptidase N plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Its function in proximal tubular epithelial cells and other cell types is less clear. The large extracellular carboxyterminal domain contains a pentapeptide consensus