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A Cyclase V/VI Polyclonal Antibody, 100ul[BT-AP00055] Antibody Humanization The encoded protein is an

SKU: 52141019733

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A Cyclase V/VI Polyclonal Antibody, 100ul[BT-AP00055] Antibody Humanization The encoded protein is anADCY5 encodes a member (adenylate cyclase 5) of the membrane bound adenylyl cyclase enzymes. Adenylyl cyclases mediate G protein coupled receptor signaling through the synthesis of the second messenger cAMP. Activity of the encoded protein is stimulated by the Gs alpha subunit of G protein coupled receptors and is inhibited by protein kinase A, calcium and Gi alpha subunits. Single nucleotide polymorphisms in this gene may be associated with low birth

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Description

The encoded protein is an inhibitor of the receptor-transduced mitogen-activated protein kinase (MAPK) signaling pathway

which are implicated in actin remodeling

PML is often involved in the translocation with the retinoic acid receptor alpha gene associated with acute promyelocytic leukemia (APL)

It is sensitive to such diuretics as furosemide and bumetanide

A Cyclase V/VI Polyclonal Antibody, 100ul[BT-AP00055] Antibody Humanization The encoded protein is anADCY5 encodes a member (adenylate cyclase 5) of the membrane bound adenylyl cyclase enzymes. Adenylyl cyclases mediate G protein coupled receptor signaling through the synthesis of the second messenger cAMP. Activity of the encoded protein is stimulated by the Gs alpha subunit of G protein coupled receptors and is inhibited by protein kinase A, calcium and Gi alpha subunits. Single nucleotide polymorphisms in this gene may be associated with low birth

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