EGFR Polyclonal Antibody, 100ul[BT-AP02862] Organelle Studies The N-terminal portion is transported

The N-terminal portion is transported to the nucleus where it homodimerizes to form the active kinase which promotes the condensation of chromatin during apoptosis

IRF2 also functions as a transcriptional activator of histone H4

The encoded protein functions as a homodimer and binds to the inverted palindrome 5'-GTTAATNATTAAC-3'

and it is activated by Myc protein

EGFR Polyclonal Antibody, 100ul[BT-AP02862] Organelle Studies The N-terminal portion is transportedEpidermal growth factor receptor encoded by EGFR is a transmembrane glycoprotein that is a member of the protein kinase superfamily. Epidermal growth factor receptor is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of tepidermal growth factor receptor to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation.