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Ref-1 Polyclonal Antibody, 50ul[BT-AP07734] Sample Library Tubes the encoded protein binds a

SKU: 53596928224

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Ref-1 Polyclonal Antibody, 50ul[BT-AP07734] Sample Library Tubes the encoded protein binds aApurinic apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. APEX1 encodes the major AP endonuclease in human cells.

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Description

the encoded protein binds a p85 regulatory subunit to form PI3K

coupling the SUMO conjugating enzyme Ubc9 with its substrate proteins

This technology has been widely applied in fundamental research

In addition to its role in regulating the later stages of terminal differentiation of keratinocytes

Ref-1 Polyclonal Antibody, 50ul[BT-AP07734] Sample Library Tubes the encoded protein binds aApurinic apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. APEX1 encodes the major AP endonuclease in human cells.

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