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Phospho-B23 (T199) Polyclonal Antibody, 100ul Cellular Function Assays Knockout studies in mice indicate

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Phospho-B23 (T199) Polyclonal Antibody, 100ul Cellular Function Assays Knockout studies in mice indicateNPM1 encodes a phosphoprotein which moves between the nucleus and the cytoplasm. The gene product is thought to be involved in several processes including regulation of the ARF p53 pathway. A number of genes are fusion partners have been characterized, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in this gene are associated with acute myeloid leukemia. More than a dozen pseudogenes of NPM1 have been identified.

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Description

Knockout studies in mice indicate that this gene is important for specification of paraxial mesoderm structures

AGTR1 may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium

This gene is expressed in different carcinomas

Tango1 subfamily

Phospho-B23 (T199) Polyclonal Antibody, 100ul Cellular Function Assays Knockout studies in mice indicateNPM1 encodes a phosphoprotein which moves between the nucleus and the cytoplasm. The gene product is thought to be involved in several processes including regulation of the ARF p53 pathway. A number of genes are fusion partners have been characterized, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in this gene are associated with acute myeloid leukemia. More than a dozen pseudogenes of NPM1 have been identified.

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