p63 Polyclonal Antibody, 100ul[BT-AP06845] Syringe Filter Decreased levels of Endophilin B2

Decreased levels of Endophilin B2 are found in Down Syndrome and may reflect brain dysgenesis

The protein can act as an autoantigen in pemphigus diseases

and bundling of actin filaments

At least 18 alpha and 8 beta subunits have been described in mammals

p63 Polyclonal Antibody, 100ul[BT-AP06845] Syringe Filter Decreased levels of Endophilin B2TP63 (tumor protein p63) encodes a member of the p53 family of transcription factors. The functional domains of p53 family proteins include an N terminal transactivation domain, a central DNA binding domain and an oligomerization domain. Alternative splicing of TP63 and the use of alternative promoters results in multiple transcript variants encoding different isoforms that vary in their functional properties. These isoforms function during skin