Human Interleukin 1 Receptor Antagonist, IL1RA ELISA Kit, 96T Gel & Buffers A 117 kb microdeletion at

A 117 kb microdeletion at the 5' end of the HOXD gene cluster| which includes this gene and the HOXD9-HOXD13 genes| causes synpolydactyly| a dominantly inherited disease resulting in limb malformation

The protein is primarily localized to membrane-associated adherens junctions and focal adhesions but is also found at the endoplasmic reticulum and nucleus

Expression of this protein also protects cells from DNA damaging reactive oxygen species and provides some protection from DNA damage-induced apoptosis

Radial spokes| which are regularly spaced along cilia| sperm| and flagella axonemes| consist of a thin 'stalk' and a bulbous 'head' that form a signal transduction scaffold between the central pair of microtubules and dynein

Human Interleukin 1 Receptor Antagonist, IL1RA ELISA Kit, 96T Gel & Buffers A 117 kb microdeletion at