Insulin R Polyclonal Antibody, 20ul[BT-AP04565] Cell Culture Flasks The tissue distribution of the

The tissue distribution of the expressed gene suggests that it is involved in the regulation of endocrine function

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Alternative splicing produces a transcript variant encoding an isoform that is soluble rather than membrane-bound

is found in lysosomes in B cells and regulates HLA-DM-mediated peptide loading on MHC class II molecules

Insulin R Polyclonal Antibody, 20ul[BT-AP04565] Cell Culture Flasks The tissue distribution of theINSR encodes a member of the receptor tyrosine kinase family of proteins. Insulin receptor is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited