TPH1(Phospho Ser260) Polyclonal Antibody, 100ul Transporters This gene encodes a member

This gene encodes a member of the DEAD box protein family

The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing

The encoded transmembrane protein binds to SEMA3C protein {sema domain

A sequence polymorphism has been identified in the 3'UTR of the third exon

TPH1(Phospho Ser260) Polyclonal Antibody, 100ul Transporters This gene encodes a memberThis gene encodes a member of the aromatic amino acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene have been associated with an elevated risk for a variety of diseases and disorders, including schizophrenia, somatic anxiety, anger related traits, bipolar disorder, suicidal behavior, addictions, and others.