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It does this in two ways: by triggering extra insulin, a hormone that helps lower blood sugar levels, and by inhibiting glucagon, a hormone that raises blood sugar levels

401,406,407 Furthermore, the combination use of appropriate cholinesterase inhibitors, such as donepezil ( 4 ) and galantamine ( 6 ), or the combination of cholinesterase inhibitors with other neurologic drugs, metal chelators, or antioxidants, may yield surprising effects in the management of cholinergic drugs in AD, including efficacy, tolerability, and safety