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Tau(Phospho Ser262) Polyclonal Antibody, 100ul Immune Repertoire Sequencing and mutations in this gene

SKU: 72165824901

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Tau(Phospho Ser262) Polyclonal Antibody, 100ul Immune Repertoire Sequencing and mutations in this geneThis gene encodes the microtubule associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia,

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Description

and mutations in this gene have been associated with different neuromuscular diseases

It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation

including the killer cell and leukocyte Ig-like receptors

Abundant expression is detected only in reconstructed epidermis and is restricted to differentiating keratinocytes

Tau(Phospho Ser262) Polyclonal Antibody, 100ul Immune Repertoire Sequencing and mutations in this geneThis gene encodes the microtubule associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia,

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