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This gene is also the strongest candidate in the neuroblastoma tumor suppressor genes

and mitochondria

In vertebrates| this gene is linked in a head-to-head arrangement with the adjacent parkin gene| which is associated with autosomal recessive juvenile Parkinson's disease

RFA4 Polyclonal Antibody, 50ul Multiplex Immunoassays embrace the thrill of theThis gene encodes a single stranded DNA binding protein that is the 30 kDa subunit of the replication protein A complex. Replication protein A is an essential factor for DNA double strand break repair and cell cycle checkpoint activation. The encoded protein localizes to DNA repair foci and may be involved in the cellular DNA damage response. This protein may also play a role in inhibiting viral replication.