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BMAL1(Phospho-Ser42) Rabbit Polyclonal Antibody, 20ul Reservoirs CYP4F2 encodes a member of

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BMAL1(Phospho-Ser42) Rabbit Polyclonal Antibody, 20ul Reservoirs CYP4F2 encodes a member ofThe protein encoded by this gene is a basic helix loop helix protein that forms a heterodimer with CLOCK. This heterodimer binds E box enhancer elements upstream of Period (PER1 PER2 PER3) and Cryptochrome (CRY1 CRY2) genes and activates transcription of these genes. PER and CRY proteins heterodimerize and repress their own transcription by interacting in a feedback loop with CLOCK ARNTL complexes. Defects in this gene have been linked to infertility

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Description

CYP4F2 encodes a member of the cytochrome P450 superfamily of enzymes

the full length nature of one variant has not been described

Studies in mice suggest that this gene is specifically required for the differentiation of islet cells for the production of insulin| but not for the differentiation of pancreatic polypeptide-producing cells

This gene encodes a protein product localized to the lumen of the endoplasmic reticulum

BMAL1(Phospho-Ser42) Rabbit Polyclonal Antibody, 20ul Reservoirs CYP4F2 encodes a member ofThe protein encoded by this gene is a basic helix loop helix protein that forms a heterodimer with CLOCK. This heterodimer binds E box enhancer elements upstream of Period (PER1 PER2 PER3) and Cryptochrome (CRY1 CRY2) genes and activates transcription of these genes. PER and CRY proteins heterodimerize and repress their own transcription by interacting in a feedback loop with CLOCK ARNTL complexes. Defects in this gene have been linked to infertility

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