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Nanog P8 Polyclonal Antibody, 100ul Cell Biology The protein is translocated from

SKU: 75217802004

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Nanog P8 Polyclonal Antibody, 100ul Cell Biology The protein is translocated fromThis locus is a processed pseudogene of the transcription factor NANOG. NANOG plays a central role in regulating self renewal in pluripotent stem cells and tumor cells. This pseudogene contains an intact open reading frame that could potentially encode a protein similar to NANOG. Although there is no evidence of transcription from this pseudogene, RT PCR studies suggest that NANOGP8 may be expressed in some cancer cell lines. In vitro studies using a

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Description

The protein is translocated from the Golgi apparatus to the nucleus in response to chemical anoxia and plays a role in regulation of cell death

The encoded protein has been identified as a target of auto-antibodies in the autoimmune skin blistering disease pemphigus foliaceus

More variants exist| but their full-length natures have yet to be determined

PNPLA8 encodes a member of the patatin-like phospholipase domain containing protein family

Nanog P8 Polyclonal Antibody, 100ul Cell Biology The protein is translocated fromThis locus is a processed pseudogene of the transcription factor NANOG. NANOG plays a central role in regulating self renewal in pluripotent stem cells and tumor cells. This pseudogene contains an intact open reading frame that could potentially encode a protein similar to NANOG. Although there is no evidence of transcription from this pseudogene, RT PCR studies suggest that NANOGP8 may be expressed in some cancer cell lines. In vitro studies using a

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