Desmin Monoclonal Antibody(1B12), 20ul Immune Repertoire Sequencing Diacylglycerol kinase alpha encoded by

Diacylglycerol kinase alpha encoded by DGKA belongs to the eukaryotic diacylglycerol kinase family

Inhibits SIRT1 deacetylase activity leading to increasing levels of p53/TP53 acetylation and p53-mediated apoptosis

4-linked N-acetylgalactosamine (GalNAc) flanked by glucuronic acid residue in chondroitin

The peptide binding cleft accommodates peptides of 10-30 residues

Desmin Monoclonal Antibody(1B12), 20ul Immune Repertoire Sequencing Diacylglycerol kinase alpha encoded byThis gene encodes a muscle specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.