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SMRTe Polyclonal Antibody, 20ul Peptide Modification Mutations in NPM1 are associated

SKU: 76239167177

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SMRTe Polyclonal Antibody, 20ul Peptide Modification Mutations in NPM1 are associatedNCOR2 (nuclear receptor corepressor 2) encodes a nuclear receptor co repressor that mediates transcriptional silencing of certain target genes. The encoded protein is a member of a family of thyroid hormone and retinoic acid receptor associated co repressors. This protein acts as part of a multisubunit complex which includes histone deacetylases to modify chromatin structure that prevents basal transcriptional activity of target genes. Aberrant

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Description

Mutations in NPM1 are associated with acute myeloid leukemia

resulting in the inhibition of proteolytic activity

Several transcript variants are resulted from alternative splicing of SIRT2

DNA pol Ω is ubiquitously expressed in various tissues and mediates the cellular mechanism of damage-induced mutagenesis

SMRTe Polyclonal Antibody, 20ul Peptide Modification Mutations in NPM1 are associatedNCOR2 (nuclear receptor corepressor 2) encodes a nuclear receptor co repressor that mediates transcriptional silencing of certain target genes. The encoded protein is a member of a family of thyroid hormone and retinoic acid receptor associated co repressors. This protein acts as part of a multisubunit complex which includes histone deacetylases to modify chromatin structure that prevents basal transcriptional activity of target genes. Aberrant

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