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HSF2B Rabbit Polyclonal Antibody, 100ul Gloves Its two SH3 domains direct

SKU: 77391069802

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HSF2B Rabbit Polyclonal Antibody, 100ul Gloves Its two SH3 domains directHSF2 binding protein (HSF2BP) associates with HSF2. The interaction occurs between the trimerization domain of HSF2 and the amino terminal hydrophilic region of HSF2BP that comprises two leucine zipper motifs. HSF2BP may therefore be involved in modulating HSF2 activation.

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Description

Its two SH3 domains direct complex formation with proline-rich regions of other proteins

Protein S100-A10 encoded by S100A10 is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs

serve as receptors for globular and full-length adiponectin (MIM 605441) and mediate increased AMPK (see MIM 602739) and PPAR-alpha (PPARA

Mutations in this gene cause nephronophthisis (NPHP)| an autosomal recessive kidney disease characterized by tubular basement membrane disruption| interstitial lymphohistiocytic cell infiltration| and development of cysts at the corticomedullary border of the kidneys

HSF2B Rabbit Polyclonal Antibody, 100ul Gloves Its two SH3 domains directHSF2 binding protein (HSF2BP) associates with HSF2. The interaction occurs between the trimerization domain of HSF2 and the amino terminal hydrophilic region of HSF2BP that comprises two leucine zipper motifs. HSF2BP may therefore be involved in modulating HSF2 activation.

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