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GLP-1 peptide Cagrilintide's changing clinical profile opens the door for new combination drugs that might have better patent protection, but they need bigger spending in clinical validation

If in stable fractures the intervertebral disc can be retained, it would be necessary to assess the individual risk factors for a degenerative course and to elucidate the value of temporary instrumentation and stress-shielding of the disc after trauma as well as of posttraumatic loading

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