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JAK1 Polyclonal Antibody, 100ul[BT-AP04683] Enzyme-Linked Immunosorbent Assay (ELISA) DNA ligase 3 encoded by

SKU: 79450152685

4.6
SEK123.75 SEK168.75

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JAK1 Polyclonal Antibody, 100ul[BT-AP04683] Enzyme-Linked Immunosorbent Assay (ELISA) DNA ligase 3 encoded byJAK1 encodes a membrane protein that is a member of a class of protein tyrosine kinases (PTK) characterized by the presence of a second phosphotransferase related domain immediately N terminal to the PTK domain. The encoded kinase phosphorylates STAT proteins (signal transducers and activators of transcription) and plays a key role in interferon alpha beta and interferon gamma signal transduction. Alternative splicing results in multiple transcript

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Description

DNA ligase 3 encoded by LIG3 is involved in excision repair and is located in both the mitochondria and nucleus

The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis

Multiple transcript variants encoding different isoenzymes have been identified for this gene| some of which have failed to demonstrate significant oxidase activity on natural polyamine substrates

cell division

JAK1 Polyclonal Antibody, 100ul[BT-AP04683] Enzyme-Linked Immunosorbent Assay (ELISA) DNA ligase 3 encoded byJAK1 encodes a membrane protein that is a member of a class of protein tyrosine kinases (PTK) characterized by the presence of a second phosphotransferase related domain immediately N terminal to the PTK domain. The encoded kinase phosphorylates STAT proteins (signal transducers and activators of transcription) and plays a key role in interferon alpha beta and interferon gamma signal transduction. Alternative splicing results in multiple transcript

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