DnaJC17 Polyclonal Antibody, 50ul Stepper CDKL3 was identified as a

CDKL3 was identified as a gene absent in leukemic patients with chromosome 5q deletion

The encoded protein (trafficking protein particle complex 3) participates in the regulation of transport from the endoplasmic reticulum to the Golgi apparatus

Inhibits SIRT1 deacetylase activity leading to increasing levels of p53/TP53 acetylation and p53-mediated apoptosis

No other protein can be recognized by this antibody from the sequence BLAST results

DnaJC17 Polyclonal Antibody, 50ul Stepper CDKL3 was identified as aThe DnaJ family is one of the largest of all chaperone families and has evolved with diverse cellular localization and functions. The presence of the J domain defines a protein as a member of the DnaJ family. DnaJ heat shock induced proteins are from the bacterium Escherichia coli and are under the control of the htpR regulatory protein. The DnaJ proteins play a critical role in the HSP 70 chaperone machine by interacting with HSP 70 to stimulate ATP