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p57 (Acetyl Lys278) Polyclonal Antibody, 100ul Cell Culture Plates and the second one lacks

SKU: 86626001200

4.2
EUR141.00 EUR169.00

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p57 (Acetyl Lys278) Polyclonal Antibody, 100ul Cell Culture Plates and the second one lacksCDKN1C is imprinted, with preferential expression of the maternal allele. Cyclin dependent kinase inhibitor 1C is a tight binding, strong inhibitor of several G1 cyclin Cdk complexes and a negative regulator of cell proliferation. Mutations in CDKN1C are implicated in sporadic cancers and Beckwith Wiedemann syndorome, suggesting that CDKN1C is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for

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Description

and the second one lacks the essential Glu active site residue at position 889

A similar protein in mouse has been reported to play a role in liver organogenesis

Boost your transcription game with the Hi-yield T7 in vitro reagent

The first mRNA transcript isolated for GCFC2 (GC-rich sequence DNA-binding factor 2) was part of an artificial chimera derived from two distinct gene transcripts and a primer used in the cloning process (see Genbank accession M29204)

p57 (Acetyl Lys278) Polyclonal Antibody, 100ul Cell Culture Plates and the second one lacksCDKN1C is imprinted, with preferential expression of the maternal allele. Cyclin dependent kinase inhibitor 1C is a tight binding, strong inhibitor of several G1 cyclin Cdk complexes and a negative regulator of cell proliferation. Mutations in CDKN1C are implicated in sporadic cancers and Beckwith Wiedemann syndorome, suggesting that CDKN1C is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for

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