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PDGFR-Beta Polyclonal Antibody, 100ul[BT-AP07023] Buffer Solutions Mutations in this gene have

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PDGFR-Beta Polyclonal Antibody, 100ul[BT-AP07023] Buffer Solutions Mutations in this gene havePDGFRB encodes a cell surface tyrosine kinase receptor for members of the platelet derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes

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Description

Mutations in this gene have been associated with obesity and pituitary dysfunction

An important paralog of this gene is CCDC102B

mismatch repair system component is thought to be involved in the repair of DNA mismatches

The protein is a ubiquitin ligase that functions in the endoplasmic reticulum-associated degradation pathway

PDGFR-Beta Polyclonal Antibody, 100ul[BT-AP07023] Buffer Solutions Mutations in this gene havePDGFRB encodes a cell surface tyrosine kinase receptor for members of the platelet derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes

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