TOP2A(Phospho Ser1213) Rabbit Polyclonal Antibody, 20ul Cell Dissociation Mutations in this gene cause
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TOP2A(Phospho Ser1213) Rabbit Polyclonal Antibody, 20ul Cell Dissociation Mutations in this gene causeCatalytic activity: ATP dependent breakage passage and rejoining of double stranded DNA. enzyme regulation: Specifically inhibited by the intercalating agent amsacrine. Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double strand breaks. miscellaneous: Eukaryotic topoisomerase I and II can relax both negative and positive supercoils whereas prokaryotic enzymes relax only
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