DDX8 Polyclonal Antibody, 20ul Buffer Solutions Mutations in TP53 are associated

Mutations in TP53 are associated with a variety of human cancers

and neonatal-onset multisystem inflammatory disease (NOMID)

Alternative splicing of this gene results in two transcript variants encoding different isoforms

this protein contains transducin-like repeats

DDX8 Polyclonal Antibody, 20ul Buffer Solutions Mutations in TP53 are associatedDHX8 is a member of the DEAH box polypeptide family. DEAH box helicase 8 contains the DEAH (Asp Glu Ala His) motif which is characteristic of all DEAH box proteins, and is thought to function as an ATP dependent RNA helicase that regulates the release of spliced mRNAs from spliceosomes prior to their export from the nucleus. This protein may be required for the replication of human immunodeficiency virus type 1 (HIV 1). Alternative splicing results in