ErbB-3 Monoclonal Antibody, 100ul[BT-MCA0503] Insect Expression The protein encoded by MAP3K1

The protein encoded by MAP3K1 (mitogen-activated protein kinase kinase kinase 1) is a serine/threonine kinase and is part of some signal transduction cascades

GTPase-activating proteins

Alternatively spliced transcript variants encoding different isoforms found for this gene

Binding of the encoded protein to complement proteins accelerates their decay

ErbB-3 Monoclonal Antibody, 100ul[BT-MCA0503] Insect Expression The protein encoded by MAP3K1This gene encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the