Zic1/2/3/4/5 Polyclonal Antibody, 50ul Cell Senescence CLIP2 is hemizygously deleted in

CLIP2 is hemizygously deleted in Williams syndrome

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It is a transcriptional repressor of genes that require a bHLH protein for their transcription

and the kinase activity of the complex is regulated throughout the cell cycle mainly by fluctuating levels of Dbf4

Zic1/2/3/4/5 Polyclonal Antibody, 50ul Cell Senescence CLIP2 is hemizygously deleted inZIC1 (Zic family member 1) encodes a member of the ZIC family of C2H2 type zinc finger proteins. Members of this family are important during development. Aberrant expression of ZIC1 is seen in medulloblastoma, a childhood brain tumor. ZIC1 is closely linked to the gene encoding zinc finger protein of the cerebellum 4, a related family member on chromosome 3. ZIC1 encodes a transcription factor that can bind and transactivate the apolipoprotein E gene.